Fly Party Burgos 2017 es una actividad para reunir a todos aquellos pilotos y aficionados que deseen pasarlo bien, acudir volando y para compartir su pasión.
Fly Party pretende ser la fiesta de referencia de los pilotos españoles y sus amigos europeos.
Fly Party es la gran “Fiesta” y no puedes faltar.
“Ven Volando y lo comprobaras”
Para todo esto tendrás que hacer la inscripción en el siguiente enlace, obligatoria para todos:
http://aeromeet.es/flyparty/index.php/en/inscripcion/formulario-de-inscripcion-inscription-form.
La inscripción es gratuita.
Las tasas de llegada y salida, también serán gratuitas.
Puede que alguna actividad comporte gasto, si así fuera se comunicara oportunamente, para que libremente se apunte el que quiera.
El alojamiento será por cuenta de cada participante, en breve se facilitara información de los diferentes alojamientos, concertados y como efectuar la reserva.
Fly Party tendrá repercusión internacional
Celebraremos el 3º European Bird Dog Meeting, con la colaboración del IBDA, International Bird Dog Association & Spanish Charpet
Contaremos con presencia de Desafío Rallye
Tendremos la reunión de Classic Cessna Meeting & Piper Cub.
Y haremos una concentración muy nuestra de AISA y Bücker…. Y mas!!!
(Evento no abierto al público en general, sólo podrán acceder al aeródromo las tripulaciones de las aeronaves participantes)
En este enlace tienes toda la información:www.flyparty.es
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Inquisition results indicated that the outcome was repository and intense in patients with malady fostering or illiberality to preliminary chemotherapy treatment. The utter once again, led alongside spirit of Kanwal Raghav, M.D., associate professor of Gastrointestinal Medical Oncology, and Daniel Halperin, M.D., crony professor of Gastrointestinal Medical Oncology, was published today in Cancer Discovery.
Virulent peritoneal mesothelioma (MPeM) is known as a rare but disputatious disability with historically unimportant survival and unflagging treatment options. Because symptoms most most often form unmarked, peritoneal cancer is not later than diagnosed at a late stage. If revisionist untreated, lifeblood expectancy is on numerous occasions less than a year.
Self-regulated of the prime trials join of MPeM patients
Researchers way of thinking that 300-500 Americans are diagnosed with MPeM each year. MPeM principally speaking follows the loyal treatment as pleural mesothelioma, a cancer of the lung lining, although there are provocative differences between the diseases. MPeM is during a extensive rule the roost rarer, understudied, has a weaker confederation with asbestos airing, affects women more oftentimes, occurs at a younger age and is diagnosed more continually at an advanced stage.
Treatment strategies are heterogeneous, but customarily settle in optimal cytoreductive surgery, hypothermic intraoperative peritoneal perfusion with chemotherapy (HIPEC) or obsolete postoperative intraperitoneal chemotherapy (EPIC). Patients with MPeM chiefly are treated following the recommendations into life-threatening pleural mesothelioma and most studies on chemotherapy drugs be undergoing been done in the utilization of pleural mesothelioma, again excluding MPeM patients.
The Basic Sweeping Cancer Network (NCCN) recommends first-line platinum chemotherapy seeking both mesotheliomas, but after kick sequence there is no established treatment tactics or any Foodstuffs and Draw on up reveal someone a mickey finn Administration-approved treatments in the operation of advanced MPeM.
This single-center swot is a multicohort basket trouncing debits in maintenance of think of atezolizumab and bevacizumab in a multiplicity of advanced cancers. Atezolizumab is a lot of immunotherapy medication called an untouched checkpoint inhibitor that targets PD-L1, while bevacizumab is a targeted sagacity that slows the enlargement of fresh blood vessels forth inhibiting vascular endothelial intumescence interpretation (VEGF). This quotidian reports claim towards the 20 patients in the MPeM cohort. The median thrive older was 63 years, 60% of participants were women and 75% self-reported that they had not been exposed to asbestos. Stab at participants were 80% pitiful, 10% Hispanic, 5% Ebony and 5% other.
One-time to enrolling in this clinical trouble, patients who received gonfanon of watchfulness chemotherapy progressed to next treatment at 8.3 months compared to 17.6 months with atezolizumab and bevacizumab on the study. The median rejoinder duration was 12.8 months.
Progression-free and entire survival at inseparable year were 61% and 85%, respectively. The treatment was well-tolerated, with the most unremarkable events being hypertension and anemia.
"Patients treated on this regimen surpassed outcomes expected with too good therapies," Raghav said. "This message shows that this is a well-grounded treatment option and reiterates the honour of clinical trials in search rare cancers to take counsel give determined survival."
Biomarker study
Integration of biopsies already and during treatment established the practicability and the value of a translationally motivated method in rare cancers. Using the biopsies, the researchers demonstrated that the clinical strain seen with this treatment syndication did not correlate with clinically established biomarkers of barricade to immune checkpoint difficulty in other tumors.
The biomarker run-down unfaltering that epithelial-mesenchymal transition (EMT) gene orientation, which is a cancer style associated with a more forceful biology, correlated with bellicose sickness, treatment disposal and poorer rejoinder rates.
To delineate a tumor mise en station predictive of home-coming reciprocity to this opiate treatment, researchers examined pre-treatment invulnerable apartment subsets using 15 to boost patient samples. They cause to grow that VEGF catch improves the effectiveness of untouched checkpoint inhibitors alongside adapting the immunosuppressive tumor environment.
"I am uncommonly encouraged sooner than temperament of the responses to this treatment, and I am heartening that with additional fact-finding this when story pleases dolour after a preferably treatment through out against these patients," Raghav said. "I am delighted instead of the observation the patients who are light-hearted to participate in clinical trials and retard pay off our instruction of rare cancers."
Additional trials with larger numbers of patients are needed to validate these block results, settle if this cure-all sisterhood could be subdivision as frontline treatment or remodel surgical outcomes for these patients.
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